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Parkinsonn's Supplement
with Mucuna powder

Only 1 teaspoon, twice a day,

That's all you need


Disclaimer: individual results may vary

Mannitol with Mucuna | Parkinson's supplements


About our Mannitol
mannitol information
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A natural supplement for degenerative diseases of the central nervous system

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Do you take more and more medications in an attempt to manage the condition? 

Well, here's a crucial information you should know:

Medication Doesn't treat the cause of Parkinson's, It only treats the symptoms!

The Cause: Protein called Alpha-Synuclein.

This protein is abundant in the human brain and gradually destroys the brain cells that produce the primary chemical molecule that sends signals to other parts of the brain for the control of movement, coordination and some form of thought.

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New research has found a solution to this alpha-synuclein clumps!
The research identified a molecule

that can prevent and reduce
alpha-synuclein aggregates.

This molecule is the Mannitol! 
It is actually a natural treatment
for Parkinson's. Studies have shown that mannitol is able to reduce the formation of these lumps by about 70% percent.

Read about our Unique Mannitol formula:
Homeotreat developed a unique MANNITOL powder, containing, not only the natural sweetener (Made from vegetables such as onions, pumpkin, seaweed, mushrooms and more), which causes a decrease in the production of the alpha-synuclein protein but also the MUCUNA plant, which supports the increase in the amount of essential ingredients to healthy brain function.

This Mannitol unique formula can help alleviate the symptoms of this cunning disease.

Mannitol has a variety of uses and it is also used to reduce elevated pressure in the brain (Central oedema) and in the eyes. Mannitol is a common low-calorie sweetener approved by the FDA and EFSA.

It has been proven to be a contributory factor in the symptoms of Parkinson's disease, along with being a natural alternative sweetener to sugar. Mannitol is a natural sweetener that is a sugar substitute in food products, for people suffering from diabetes or for people who are aware of a healthy lifestyle and reduced use of processed sugar.
In Parkinson's, nerve damage occurs in the brain. It is known that these processes result from the crystallization of alpha-synuclein protein. Studies have shown that mannitol has a 70% effect on reducing the formation of these lumps.
The velvet bean - Mucuna, helps as a rich and available source of dopamine to supply the body with the lack of existing dopamine, at the same time as the action of mannitol.

Mannitol with Mucuna | Parkinson's supplements

Mannitol Powder

Contains 10% Mucuna

Natural Effective Treatment

No side effects

Safe, Tested & Proven

Relieve Symptoms

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"Parkinson's patients who consume Mannitol, report improvements in both motor and non-motor symptoms".

Taken from
Man Rev

People Like You

Tania | Mannitol reviews

Tania D. Barrie, CA

"I'm taking one teaspoon a day for the last 3 months and I'm getting better every day, although it is a slow improvement. I got my voice back,  can speak loud and clear, There was a radical improvement in the quality of my sleep, and I can now use less medication and less Mannitol"

Josh | Mannitol Testimonial

Josh B. Jerusalem, Israel

"Listen, this Mannitol powder saved my life. Before using it, I used costly medications which had side effects and I was really depressed, After using your Mannitol treatment I feel that I want to leave again. My leg pain leg ceased, I got back my smell sense, I could sleep well, and I could finally use fewer medications "

Mannitol review | Danny

Danny S. FL, USA

"The medications did not help me, but your natural product saved me! I call it "natural cure for parkinson's disease". I feel much better, and I can surely say that this is the best treatment for Parkinson's.


Mannitol review | Robet

Robert K. PA, USA

"I was diagnosed with Parkinson’s and struggled with severe pain in my extremities. I have been on Top Probiotics’s Mannitol product for approximately three months and my pain is largely gone! It appears to me my pain relief is from this product! It has made a major difference in the quality of my life! ALL FOR THE BETTER!!!"

Portrait of a Senior Man

George N.  Canada

"I first bought this mannitol about a year ago, and I'm using it since then on a daily basis (3 times a day). Mannitol made me feel vital, my sense of taste improved immeasurably, my sleep is now deep and good, the pain is gone, and the tremors were significantly reduced. I know I have not been cured but thanks to the Mannitol I feel much better. Thank you very much"

Old Asian Man

Alex M, London, UK

"I purchased the mannitol for my mom and I definitely highly recommend it. It is very helpful in relieving symptoms and relieving pain significantly.
I will buy again and again :-)
Thank you very much !!!

Happy Old Man

Yuval C. TLV, IL

"To Whom It May Concern,
My dear father had unbearable tremors in his hands mainly while eating. We tried almost everything to solve the problem (coconut oil and more ..) until we got this Mannitol.
After several days of using it, to our surprise, the tremors stopped.
After about 3 months of use, we stopped taking the Mannitol, but after a few weeks, the tremors gradually returned.
We decided to take the Mannitol again and resolved the hand tremors issue".


Ray F. Ohio, USA

"I purchased the mannitol for my mom and I definitely highly recommend it. It is very helpful in relieving symptoms and relieving pain significantly.
I will buy again and again :-)
Thank you very much !!!

Change your everyday life guaranteed

Mannitol Best Treatment

Mannitol can change your everyday life guaranteed.
We, at Homeotreat have been Mixing the Knowledge for 20 years and passing it to thousands of practitioners worldwide.



While medications do not have the ability to penetrate the blood barrier, the researchers recommend using mannitol in conjunction with other approved medications because of the proven ability of mannitol to penetrate the barrier and to allow for the passageway of beneficial compounds from the proven drugs for effective treatment of Parkinson's disease.

Many people have already experienced improvements in their symptoms by using Mannitol.  

Directions: 2 teaspoons a day (about 10 grams daily dose).
Easy to use: Mannitol can be used as a sweetener for hot or cold drinks.

Buy Mannitol Now
Mannitol with Mucuna | Parkinson's supplements

300 gr.


2-pack of Mannitol with Mucuna | Parkinson's supplements

600 gr.


3-pack of Mannitol with Mucuna | Parkinson's supplements

900 gr.



Our Unique MANNITOL powder Formula Includes also 10% MUCUNA
In a special pet jar, preventing any radiation and moisture

Net Wt: 300g (10.6 oz)

Man Ing


What is Mannitol?
a natural alcoholic sugar was recently suggested as a potential disease-modifying agent in Parkinson's disease. In animal models of the disease, mannitol interferes with the formation of α-synuclein fibrils, inhibits the formation of α-synuclein oligomers, and leads to
phenotypic recovery of impaired motor functions. Parkinson's patients who consume mannitol report improvements in both motor and non-motor symptoms. The safety of long-term use of oral Mannitol, tolerable dose, and possible benefit, however, was never clinically studied. We studied the safety of oral mannitol in Parkinson's disease and assessed the maximal tolerable oral dose by conducting a phase IIa, randomized, double-blind, placebo-controlled, single-center, dose-escalating study ( Identifier: NCT03823638). The study lasted 36 weeks and included four dose escalations of oral mannitol or dextrose to a maximal dose of 18 g per day. The primary outcome was the safety of oral mannitol, as assessed by the number of adverse events and abnormal laboratory results. Clinical and biochemical efficacy measures were collected but were not statistically powered. Fourteen patients receiving mannitol completed the trial (in addition to eight patients on placebo). Mannitol-related severe adverse events were not observed.
Gastrointestinal symptoms limited dose escalation in 6/14 participants on mannitol. None of the clinical or biochemical efficacy secondary outcome measures significantly differed between groups.
We concluded that long-term use of 18 g per day of oral mannitol is safe in Parkinson's disease patients but only two third of patients tolerate this maximal dose. These findings should be considered in the design of future efficacy.


What is Mucuna Pruriens (MP)? 
MP also referred to as the velvet bean, is a legume that grows in tropical and subtropical areas across the world including Africa, Asia, the Caribbean, and the Pacific Islands. Although the beans can be used as a source of food after they are boiled, MP is also a medicinal plant, used for millennia in traditional Ayurvedic Indian medicine, for a variety of conditions. MP has been investigated for its anti-diabetic, anti-microbial, anti-oxidant, antiepileptic, and anti-depressant properties, to name a few.
Because it contains 6-9% levodopa by weight, however, one of its main medicinal uses is to counteract parkinsonian symptoms.

Mucuna | Velvet Bean

Mucuna | Velvet Bean

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Professional articles about Mannitol

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“it acts as a molecular chaperone — a type of molecule that recognizes misfolded proteins and either shepherds them toward cellular waste disposal pathways, or initiates a refolding response."


“A Blood-Brain Barrier (BBB) Disrupter Is Also a Potent α-Synuclein (α-syn) Aggregation Inhibitor
A Novel Dual mechanism of 
Mannitol for the treatment of Parkinson disease (PD)”


“56% report improvement in their Parkinson's symptoms”

”Patients show greater improvement the longer they took Mannitol"

(Clinicrowd Webinar, March, 25th, 2018)

Why is it so important to add Brain-770 along with Mannitol?

While Mannitol prevents the formation of alpha-synuclein protein clumps, Brain 770 among its other actions and benefits, can dissolve and eliminate the clumps that have already formed. This is why we highly recommend Brain 770 as a valuable supplement, not only for addressing Parkinson's disease but also for enhancing overall brain health.

BRAIN 770 is comprised of multiple components tailored to enhance the activity and functionality of the pineal gland in the brain, mitigate calcification, and hinder the crystallization of the alpha-synuclein protein, which obstructs dopamine passage to the brain's gray matter.
By significantly enhancing memory and overall quality of life, BRAIN 770 serves as a potential treatment and preventive measure against conditions like Alzheimer's disease, dementia, sclerosis, and Parkinson's disease.

BRAIN-770 | Pineal Gland calcification treatment

120 Capsules

95.00$   88.90$

Mannitol Reviews

4.7  ★★★★★


Product Reviews

Write a review 

Charles Guarisco


Excellent! My husband takes it for Parkinsonism tremors. So far we haven't noticed a decrease in the tremors. He still likes it though, because it helps him go to the bathroom easier in the morning. He wants to continue to take it to see if he gets results. The video we saw when we first looked into it said to "be patient" because it can take several months of taking this to see results.

Daniel M.


I have been using your product for over two months. I can't say that the product eliminated all the symptoms of the disease, but it definitely eased them, and that's why I continue to use it.

Paul V.


Highly recommend. I sleep better, I suffer less pain and there is even a slight improvement in tremors. Thanks. Highly recommend

Carol B.

My husband really likes this mannitol. He says it helps him. I can testify that his speech has definitely improved recently

Krishna Natarajan

Highly recommended! It works as advertised

Christian N


I was surprised with the positive results. I take it with my tea, and it helped with my tremors, with the pain, and with my sleep. Very recommended

Judith Smith


Christine Pratt


Constance C.


Just wanted to let you know that my husband has been taking the Mannitol/ Mucuna powder for several months now, and has significantly improved his quality of sleep. He has REM Sleep disorder, and takes a spoonful before bed every evening. He has a hand tremor, and has been told by a neurologist he may develop Parkinson's over the next 5 years. We wanted to be proactive, so I went online and found your product. We have been very happy about the results! He went from thrashing about and acting out his dreams 3 times per month, to once every other month- and now it is much milder when it does happen. We are very happy with your product and hope that it can provide some measure of slowing down the onset of Parkinson's. thank you very much!

Izabela C.


Very good!

Christopher R.


I'm satisfied
I'm taking it for a while, and I feel a slight improvement (Which is very satisfying for me). Hope it will get even better soon.

Joseph O.

5 ★★★★★

I Recommend this Mannitol

5 ★★★★★

Expensive but good! I don’t like that I should pay import duties In Canada every time I'm ordering it, but I do like the product – It reduced my symptoms.

Mia C.


I bought it to my grandma 3 weeks ago– She likes it & it seems that she's having a physical improvement.

Lucas W.


Not so satisfied. Took a whole jar and felt only slight improvement.

Benjamin S.


Exactly as described, high quality, fast delivery. Good!

Amelia R.


I think it helped me to stop the worsening processes of the disease. I have been taking Mannitol for a few weeks now, and I feel a bit better, and there is no further deterioration in my condition. I think it is the best I can do now, and I like it.

Josh T.


Highly recommended! It helped me a lot.

Miriam G.


This is a good quality product. I've been trying some other before, but this one is the best I had. Very recommended, and very helpful. My day to day life feels much better.

Oren C.

5 ★★★★★

I order this product regularly - very good! I'm having it with my Coffee.

Jerry B.

5 ★★★★★

Good product, I like it, excellent customer support, Thanks!

Michael E

5 ★★★★★

Arrived fast, and it has Mucuna inside, so results are a bit faster. I'm satisfied.

Max H.

5 ★★★★★

I am a repeat customer, and overtime the treatment has been helpful.

Michael E

5 ★★★★★

Arrived fast, and it has Mucuna inside, so results are a bit faster. I'm satisfied.

Jasmin A.

5 ★★★★★

My husband uses this Mannitol to reduce his Parkinson's symptoms. I can see an improvement with his sleep and voice, and maybe a bit with his tremor. He likes it, and seems to work for him.


3 ★★★

Not sure yet. I'm taking this product for 2 weeks now and it is almost like every natural sweetener – Easy to use, I like it. I didn't feel any improvement yet, but according to the studies I've read, it might take a while. Hope to update soon

Tim A.

5 ★★★★★

Certainly helped me
I've been taking this Mannitol for a few months, so far, I find it very helpful.


5 ★★★★★

I first bought this mannitol about a year ago, and I'm using it since then on a daily basis (3 times a day). Mannitol made me feel vital, my sense of taste improved immeasurably, my sleep is now deep and good, the pain is gone, and the tremors were significantly reduced. I know I have not been cured but thanks to this Mannitol I feel much better. Thank you very much


Robert N.

5 ★★★★★

I was diagnosed with Parkinson’s and struggled with severe pain in my extremities. I have been on Top-Probiotics Mannitol product for approximately three months and my pain is largely gone! It appears to me that my pain relief is from this product! It has made a major difference in the quality of my life! ALL FOR THE BETTER!!!

David V

5 ★★★★★

I've been taking Mannitol for 10 weeks. At the first 4 weeks, I've got relief from going to the toilets. At the next few weeks, my voice became clearer and loud. The Mannitol helped me, but you have to be patience for getting results.

More reviews
  • How to use HelicoBacstop?
    You should take 2 capsules a day One in the morning and the second one in the evening, on an empty stomach* (*60 minutes before a meal, or 2 hours after a meal)
  • How would I know that Helico-Bacstop helped me?
    After a month of taking HelicoBacstop, you should make another breathing test and compare between the results before the reatment, and after - You'll see a major improvement
  • Will I feel any improvement by using Helico Bacstop?
    Yes! Helico-Bacstop reduces the bacteria by 80% (To its minimum necessary amount). You should feel much better once using Helico-Bacstop.
  • Can I eat everything while taking Helico-Bacstop?
    In order to get the best results, you should avoid pastries and dough, fried foods, smoked foods, dairy products, white flour bread, and tomatoes during and after treatment
  • How long does it take to HelicoBacstop to start working?
    Within a few days of taking the HelicoBacstop, you'll feel much better and the symptoms you were feeling prior to using it, will begin to notably dissipate.
  • Can I take Helico Bacstop along, or after taking antibiotics?"
    Yes, you can take the Helico Bacstop along, or after taking antibiotics

About US

Mannitol is manufactured by Homeotreat (Since 1997) - An Israeli company specialized in developing natural & effective products that provide a wide range of natural solutions to improve the quality of life. Both research and development, as well as production and packaging, are made by Homeotreat, in Israel.

The company places great emphasis on the quality of the products and their development processes. These processes are of great importance and therefore many resources are invested in thorough research and the quality of the raw materials.
The manufacturing and packaging processes are carried out under the GMP & ISO certification and upon the supervision of the Israeli Ministry of Health.


We ship worldwide.

All our products are shipped from Israel.
Due to the COVID-19 crisis, we can not offer regular free shipping service. All orders will be shipped with an Expedited/express shipping service - Shipping 
usually takes 3-6 business days (Shipping fees will be calculated at the checkout).

Handling time may take up to 2 business days.
Kindly be aware that packages sent to customers outside of the United States might incur a customs fee upon the package's arrival in the recipient's country.

Please note that we are not responsible for any delays or duties caused by customs at the recipient country.

Contact Us

IF you have any questions regarding Mannitol (Parkinson's treatment), please don't hesitate to contact us:

Thanks! Message sent.

Disclaimer: individual results may vary

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